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Failed skin graft and flaps

medical indications


Failed skin grafts and flaps



Skin graft – a segment of skin separated completely from its bed and transplanted to another site.
Flap – tissue (skin and subcutaneous) transferred from one site to another with intact vascular supply or attached to donor site vessels.

Many factors can contribute to necrosis of skin grafts and flaps such as;
In flaps - ischemia, edema, hematoma, arterial vasospasm, arterial or venous occlusion, thrombosis and infection.
In grafts – improper recipient wound (hypoxic, infected and without adequate granulation (healthy) tissue formation.
All above described are leading to failure of skin grafts and flaps and are associated with increased morbidity, repetition of surgical procedures and hospitalization.

Clinical application of HBO:


Benefits of hyperbaric oxygen therapy in survival of skin grafts and flaps are:

       


References:

  1. Angel MF, Im MJ, Chung HK, Vander Kolk CA, Manson PN:  Effects of combined cold and hyperbaric oxygen storage on free flap survival. Microsurgery; 15(9): 648-51, 1994
  2. Callan P, Jackson IT: Necrosis of flaps Plast Reconstr Surg; 98(7): 1321, Dec1996
  3. Gruber RP, Brinkley FB, Amato JJ, Mendelson JA:  Hyperbaric oxygen and pedicle flaps, skin grafts, and burns. Plast Reconstr Surg; 45(1): 24-30, Jan 1970
  4. Jiang P, Luo L:  Effects of hyperbaric oxygen on the skin graft survival Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 11(2): 91-3, Review, Mar 1997
  5. Kindwall E: Hyperbaric oxygen therapy in plastic surgery: a review article. Plast reconstr surg; 88 (5): 898-908, Nov 1991
  6. Kindwall E: Hyperbaric oxygen’s effect on radiation necrosis. Clinics in plastic surgery; 12 (3): 473-483, 1993
  7. Lozano DD, Stephenson LL, Zamboni WA: Effect of hyperbaric oxygen a medicinal leeching on survival of axial skin flaps subjected to total venous occlusion. Plast Reconstr Surg; 104(4): 1029-32, Sep 1999
  8. Mathieu D, Neviere R, Pellerin P, Patenotre P, Wattel F:  Pedicle musculocutaneous flap transplantation: prediction of final outcome by transcutaneous oxygen measurements in hyperbaric oxygen.  Plast Reconstr Sur.; 91(2): 329-34, Feb 1993
  9. McFarlane RM, DeYoung G, Henry RA:  Prevention of necrosis in experimental pedicle flaps with hyperbaric oxygen. Surg Forum; 16:481-2 1965
  10. Nylander G, Lewis D, Nordstrom H, Larsson J:  Reduction of postischemic edema with hyperbaric oxygen. Plast Reconstr Surg.; 76(4): 596-603, Oct 1985
  11. Perrins DJ:  Influence of hyperbaric oxygen on the survival of split skin grafts. Lancet; 1(7495): 868-71, Apr 22 1967
  12. Perrins JD: Influence of hyperbaric oxygen on the survival of split skin grafts. In Wada J. and  Iwa T. (eds): Proceedings of the Fourth International Congress on HBO Medicine. London: Baillere,  pp. 369-376, 1970
  13. Quirinia A, Viidik A: The influence of occlusive dressing and hyperbaric oxygen on flap survival and healing of ischaemic wounds. Scand J Plast Reconstr Surg Hand Surg; 32(1): 1-8. Mar; 1998
  14. Ramon Y, Abramovich A, Shupak A, Ullmann Y, Moscona RA, Shoshani O, Peled IJ: Effect of hyperbaric oxygen on a rat transverse rectus abdominis myocutaneous flap model. Plast Reconstr Surg; 102(2): 416-22, Aug 1998
  15. Shulman AG, Krohn HL:  Influence of hyperbaric oxygen and multiple skin allografts on the healing of skin wounds. Surgery; 62(6): 1051-8, Dec1967
  16. Stevens DM, Weiss DD, Koller WA, Bianchi DA: Survival of normothermic microvascular flaps after prolonged secondary ischemia: effects of hyperbaric oxygen. Otolaryngol Head Neck Surg; 115(4): 360-4, Oct 1996
  17. Stewart RJ, Moore T, Bennett B, et al.: Effect of free-radical scavengers and hyperbaric oxygen on random-pattern skin flaps. Archives of Surgery; 129:982-988, 1994
  18. Tai YJ, Birely BC, Im MJ, Hoopes JE, Manson PN: The use of hyperbaric oxygen for preservation of free flaps. Ann Plast Surg; 28(3): 284-7, Mar 1992
  19. Tan CM, Im MJ, Myers RA, Hoopes JE: Effects of hyperbaric oxygen and hyperbaric air on the survival of island skin flaps. Plast Reconstr Surg; 73(1): 27-3, Jan 1984
  20. Wilmeth JB, Gazaui A:  Hyperbaric oxygen as an adjunct to the treatment of orthopedic injuries with full thickness Grafts. Seventh Annual Conference on the Clinical Application of HBO, Anaheim, California, 9- 11,  June 1982
  21. Zamboni WA, Roth AC, Russell RC, Smoot EC: The effect of hyperbaric oxygen on reperfusion  ischemic axial skin flaps: a laser Doppler analysis. Ann Plast Surg; 28(4): 339-41, Apr 1992
  22. Zamboni WA, Roth AC, Russell RC, Nemiroff PM, Casas L, Smoot EC: The effect of acute hyperbaric oxygen therapy on axial pattern skin flap survival when administered during and after total ischemia. J Reconstr Microsurg; 5(4): 343-7; discussion 349-50, Oct 1989.